Madrigal Pharmaceuticals Inc. Common Stock (MDGL)

FairStock Score: 27/100 — RISKY

Key Financials

Current Price$434.24
Market Cap$10.0B
P/E Ratio-31.06
ROE-53.31%
Dividend Yield—%
SectorHealthcare

AI Analysis

AI-generated, general educational analysis — not personal investment advice.

I approach Madrigal as a Graham-style analyst, asking first what is proven and what is paid for. In fiscal Q2 2026, the quarter ended 2026-06-30, revenue was $364.3 million and net loss was $57.9 million, or $1.99 per diluted share. That revenue is impressive against fiscal Q2 2025, the quarter ended 2025-06-30, when revenue was $212.8 million, but the loss also widened from $42.3 million. For fiscal 2025, revenue was $958.4 million and net loss was $288.3 million, or $12.85 per share; fiscal 2024 revenue was $180.1 million with a $465.9 million loss. So the commercial launch is real, but profits are not. Trailing free cash flow is negative $209.3 million, a negative 2.0% yield. The FairStock calculations at the 2026-10-13 close show a price of $452.12, market cap $10.4 billion, P/B of 19.93, ROE of negative 53.31%, ROCE of negative 17.84%, and debt-to-equity of 0.66. The Piotroski F-Score is 5/9 and Altman Z-Score is 7.11, which suggests the balance sheet is not immediately fragile, but the FairStock Score of 27/100 and no Lynch category because of four straight loss years tell the same story: no earnings record. A moat in biotechnology comes from approved products, adoption, and protection from competition, and Rezdiffra's rapid sales growth is the main evidence. But I cannot call this cheap on current numbers. The stock is a bet on future profitability, not a value bargain today. I would need to see continued revenue growth and a clear path to positive earnings and cash flow.

In plain English: Madrigal sells a liver medicine called Rezdiffra for a fatty liver disease called MASH. Sales are growing fast, but the company still loses money and spends more cash than it brings in. At $452.12 a share, the price looks high compared with today's losses, so it depends heavily on future growth.

The full AI analysis, bull and bear case and key monitorables are in FairStock Pro.

Data as of 2026-10-13 close · note generated 2026-10-15 · model deepseek-flash

Sources (SEC EDGAR): fiscal Q2 2026 10-Q (period ended 2026-06-30) · fiscal Q1 2026 10-Q (period ended 2026-03-31) · fiscal Q3 2025 10-Q (period ended 2025-09-30) · fiscal Q2 2025 10-Q (period ended 2025-06-30) · FY2025 10-K (period ended 2025-12-31) · FY2024 10-K (period ended 2024-12-31) · FY2023 10-K (period ended 2023-12-31)

Fundamentals from company filings and market-data providers; prices are end-of-day, not real-time. AI-generated analysis is general and educational — not personal investment advice. Scoring methodology · Score test · Disclaimer