Iovance Biotherapeutics Inc. Common Stock (IOVA)

FairStock Score: 44/100 — MIXED

Key Financials

Current Price$14.09
Market Cap$6.4B
P/E Ratio-20.42
ROE-40.36%
Dividend Yield—%
SectorHealthcare

AI Analysis

AI-generated, general educational analysis — not personal investment advice.

Viewed through a Graham-and-Buffett lens, Iovance is a commercial-stage biotech with a promising but unproven economic engine. It sells Amtagvi and Proleukin, and filed figures show real top-line traction: in fiscal Q2 2026, the quarter ended 2026-06-30, revenue was $99.3M and net loss was $47.3M; in fiscal Q2 2025, the quarter ended 2025-06-30, revenue was $60.0M and net loss was $111.7M. For FY2025, the year ended 2025-12-31, revenue was $263.5M and net loss was $391.0M; FY2024, the year ended 2024-12-31, revenue was $164.1M; and FY2023, the year ended 2023-12-31, revenue was $1.2M. Growth is impressive, and losses are narrowing sequentially from fiscal Q1 2026’s $79.0M and fiscal Q3 2025’s $91.3M. But the business has not earned a profit in each of the last four years, so the computed Lynch category is none. FairStock calculations show negative trailing free cash flow of $296.4M, a -4.5% FCF yield, ROE of -40.36%, and ROCE of -20.31%. The balance sheet has low leverage—D/E of 0.06—and an Altman Z-Score of 17.91, but that does not create a margin of safety if cash burn continues. At the 2026-10-13 close of $14.50, market cap is $6.6B, the FairStock P/B is 8.90, and the FairStock score is 44/100. The stock has ranged from $1.76 to $15.30 over 52 weeks, so expectations are elevated. I would need evidence of a durable moat, pricing power, and a clear path to self-funding profits before calling this a Graham bargain. Today it looks more like a speculative growth story than a value investment.

In plain English: Iovance makes personalized cell therapies for melanoma and other solid tumors. Revenue is growing and losses are getting smaller, but the company still loses money and burns cash. At $14.50, the price looks rich compared with the company’s assets and cash generation, since it has no profits yet.

The full AI analysis, bull and bear case and key monitorables are in FairStock Pro.

Data as of 2026-10-13 close · note generated 2026-10-15 · model deepseek-flash

Sources (SEC EDGAR): fiscal Q2 2026 10-Q (period ended 2026-06-30) · fiscal Q1 2026 10-Q (period ended 2026-03-31) · fiscal Q3 2025 10-Q (period ended 2025-09-30) · fiscal Q2 2025 10-Q (period ended 2025-06-30) · FY2025 10-K (period ended 2025-12-31) · FY2024 10-K (period ended 2024-12-31) · FY2023 10-K (period ended 2023-12-31)

Fundamentals from company filings and market-data providers; prices are end-of-day, not real-time. AI-generated analysis is general and educational — not personal investment advice. Scoring methodology · Score test · Disclaimer