Ionis Pharmaceuticals Inc. Common Stock (IONS)

FairStock Score: 15/100 — RISKY

Key Financials

Concerns

• High leverage at 5.31x debt-to-equity increases financial risk and interest expense burden
• Currently unprofitable—sustained losses could lead to dilutive capital raises or balance sheet deterioration
• Revenue declining at 10.3% year-over-year signals potential demand weakness or market share loss
• Weak Piotroski F-Score of 3/9 suggests deteriorating financial quality across multiple dimensions

AI Analysis

Ionis Pharmaceuticals Inc. Common Stock is a mid-cap healthcare company valued at $12.3 billion. Revenue stands at $1.1 billion, though the company is currently unprofitable. From a quality standpoint, Ionis shows weak Piotroski F-Score of 3/9 signaling deteriorating fundamentals and Altman Z-Score of 2.0 in the grey zone. Growth dynamics show revenue growing at -10.3% and profit growth of -119.8%. Our composite FairStock Score of 15/100 reflects below-average fundamentals overall. Without profitability, this remains speculative—suitable only for those with high risk tolerance and a long time horizon.

Bull Case

Improving fundamentals and sector tailwinds could drive meaningful earnings growth, compressing the effective multiple for patient investors. Operational leverage in the business model means incremental revenue growth could disproportionately boost bottom-line profitability.

Bear Case

Without a clear path to profitability, continued cash burn forces either dilutive equity raises or debt accumulation that destroys shareholder value. Sluggish -10% growth in a large-cap company leaves the stock vulnerable to de-rating if the market rotates toward higher-growth opportunities.

Data from SEC filings. AI analysis is for educational purposes only — not investment advice. Scoring methodology · Disclaimer